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Proteins and Peptides

Ramipril

Product Sizes
100 mg
£ POA
HY-B0279-100MG
5 g
£ POA
HY-B0279-5G
500 mg
£ POA
HY-B0279-500MG
1 g
£ POA
HY-B0279-1G
10mM/1mL
£ POA
HY-B0279-10MM
About this Product
SKU:
HY-B0279
Additional Names:
HOE-498
CAS Number:
87333-19-5
Extra Details:
Ramipril (HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.
Molecular Weight:
416.51
Purity:
99.39
References:
[1]Raasch, W., et al., Combined blockade of AT1-receptors and ACE synergistically potentiates antihypertensive effects in SHR. J Hypertens, 2004. 22(3): p. 611-8.|[2]Stevens, B.R., M.I. Phillips, and A. Fernandez, Ramipril inhibition of rabbit (Oryctolagus cuniculus) small intestinal brush border membrane angiotensin converting enzyme. Comp Biochem Physiol C, 1988. 91(2): p. 493-7.|[3]Kohlstedt, K., et al., Angiotensin-converting enzyme is involved in outside-in signaling in endothelial cells. Circ Res, 2004. 94(1): p. 60-7.|[4]Ceconi, C., et al., Differences in the effect of angiotensin-converting enzyme inhibitors on the rate of endothelial cell apoptosis: in vitro and in vivo studies. Cardiovasc Drugs Ther, 2007. 21(6): p. 423-9.
Research Area:
Cardiovascular Disease; Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Apoptosis;Metabolic Enzyme/Protease
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