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Proteins and Peptides

Ethionamide

Product Sizes
5 g
£ POA
HY-B0276-5G
500 mg
£ POA
HY-B0276-500MG
1 g
£ POA
HY-B0276-1G
10mM/1mL
£ POA
HY-B0276-10MM
About this Product
SKU:
HY-B0276
Additional Names:
2-Ethylthioisonicotinamide
CAS Number:
536-33-4
Extra Details:
Ethionamide (2-ethylthioisonicotinamide) is a second-line anti-tuberculosis antibiotic with antibacterial effect and oral activity[1][2][3][4].
Molecular Weight:
166.25
Purity:
99.98
References:
[1]Vannelli, T.A., A. Dykman, and P.R. Ortiz de Montellano, The antituberculosis drug ethionamide is activated by a flavoprotein monooxygenase. J Biol Chem, 2002. 277(15): p. 12824-9.|[2]Quemard, A., G. Laneelle, and C. Lacave, Mycolic acid synthesis: a target for ethionamide in mycobacteria? Antimicrob Agents Chemother, 1992. 36(6): p. 1316-21.|[3]Marilyn C Henderson, et al. Metabolism of the anti-tuberculosis drug ethionamide by mouse and human FMO1, FMO2 and FMO3 and mouse and human lung microsomes. Toxicol Appl Pharmacol. 2008 Dec 15;233(3):420-7.|[4]Amy L Palmer, et al. Metabolism and pharmacokinetics of the anti-tuberculosis drug ethionamide in a flavin-containing monooxygenase null mouse. Pharmaceuticals (Basel). 2012;5(11):1147-59.
Research Area:
Infection
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Anti-infection
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