Thiabendazole
Product Sizes
5 g
£ POA
HY-B0263-5G
1 g
£ POA
HY-B0263-1G
500 mg
£ POA
HY-B0263-500MG
10mM/1mL
£ POA
HY-B0263-10MM
About this Product
- SKU:
- HY-B0263
- Additional Names:
- Tiabendazole; 2-(4-Thiazolyl)benzimidazole
- CAS Number:
- 148-79-8
- Extra Details:
- Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling[1][2][3][4][5].
- Molecular Weight:
- 201.25
- Purity:
- 99.94
- References:
- [1]Cha, H.J., et al., Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. PLoS Biol, 2012. 10(8): p. e1001379.|[2]Zhang, J., et al., Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie, 2013. 68(12): p. 962-8.|[3]Budetić M, et al. Review of Characteristics and Analytical Methods for Determination of Thiabendazole. Molecules. 2023 May 6;28(9):3926. |[4]Park J, et al. Developmental defects induced by thiabendazole are mediated via apoptosis, oxidative stress and alteration in PI3K/Akt and MAPK pathways in zebrafish. Environ Int. 2023 Jun;176:107973. |[5]Elgebaly SA, et al. Thiabendazole-induced suppression of renal damage in a murine model of autoimmune disease. Am J Pathol. 1984 May;115(2):204-11. |[6]Motwadie ME, et al. Modulation of immune functions, inflammatory response, and cytokine production following long-term oral exposure to three food additives; thiabendazole, monosodium glutamate, and brilliant blue in rats. Int Immunopharmacol. 2021 Sep;98:107902.
- Research Area:
- Cancer; Infection; Inflammation/Immunology; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection;Apoptosis;Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;Protein Tyrosine Kinase/RTK
