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Proteins and Peptides

Ipratropium (bromide) (Standard)

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HY-B0241R-1EACH
About this Product
SKU:
HY-B0241R
Additional Names:
Sch 1000 (Standard)
CAS Number:
22254-24-6
Extra Details:
Ipratropium (bromide) (Standard) is the analytical standard of Ipratropium (bromide). This product is intended for research and analytical applications. Ipratropium bromide (Sch 1000) is a muscarinic receptor antagonist; with IC50s of 2.9 nM; 2 nM; and 1.7 nM for M1; M2; and M3 receptors; respectively. Ipratropium bromide relaxes smooth muscle; can be used in the research for COPD (chronic obstructive pulmonary disease) and asthma[1][2][3][4][5].
Molecular Weight:
412.36
References:
[1]Fryer AD, et al. Maclagan, Ipratropium bromide potentiates bronchoconstriction induced by vagal nerve stimulation in the guinea-pig. Eur J Pharmacol, 1987. 139(2): p. 187-91.|[2]Harvey, et al. Maddock, Ipratropium Bromide-Mediated Myocardial Injury in In Vitro Models of Myocardial Ischaemia/Reperfusion. Toxicol Sci, 2014.|[3]Maria Prat, et al. Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinyl amides as potent and long acting muscarinic antagonists. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1736-1741.|[4]Wenhui Zhang, et al. Anti-inflammatory effects of formoterol and ipratropium bromide against acute cadmium-induced pulmonary inflammation in rats. Eur J Pharmacol. 2010 Feb 25;628(1-3):171-8.
Research Area:
Inflammation/Immunology; Neurological Disease
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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