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Proteins and Peptides

Isradipine

Product Sizes
10 mg
£ POA
HY-B0233-10MG
5 mg
£ POA
HY-B0233-5MG
50 mg
£ POA
HY-B0233-50MG
100 mg
£ POA
HY-B0233-100MG
10mM/1mL
£ POA
HY-B0233-10MM
25 mg
£ POA
HY-B0233-25MG
About this Product
SKU:
HY-B0233
Additional Names:
PN 200-110
CAS Number:
75695-93-1
Extra Details:
Isradipine (PN 200-110) is an orally active and blood-brain barrier permeability L-type calcium channel blocker. Isradipine; as a powerful peripheral vasodilator; is a dihydropyridine calcium antagonist with selective actions on the heart as well as the peripheral circulation. Isradipine is a potentially viable neuroprotective agent for Parkinson's disease[1][2][3].
Molecular Weight:
371.39
Purity:
99.97
References:
[1]Ilijic E, et al. The L-type channel antagonist isradipine is neuroprotective in a mouse model of Parkinson's disease. Neurobiol Dis. 2011;43(2):364-371.|[2]Campbell CA, et al. Effects of isradipine, an L-type calcium channel blocker on permanent and transient focal cerebral ischemia in spontaneously hypertensive rats. Exp Neurol. 1997;148(1):45-50.|[3]Hof RP, et al. Selective effects of PN 200-110 (isradipine) on the peripheral circulation and the heart. Am J Cardiol. 1987;59(3):30B-36B.
Research Area:
Cardiovascular Disease;Neurological Disease
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Autophagy;Membrane Transporter/Ion Channel;Neuronal Signaling
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