Albendazole
Product Sizes
100 mg
£ POA
HY-B0223-100MG
10mM/1mL
£ POA
HY-B0223-10MM
About this Product
- SKU:
- HY-B0223
- Additional Names:
- SKF-62979
- CAS Number:
- 54965-21-8
- Extra Details:
- Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity; is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α; VEGF expression; has antioxidant activity; and inhibits the glycolytic process in cancer cells[1][2][3][4][5].
- Molecular Weight:
- 265.33
- Purity:
- 99.05
- References:
- [1]Vural G, et al. Efficacy of novel albendazole salt formulations against secondary cystic echinococcosis in experimentally infected mice. Parasitology. 2020 Nov;147(13):1425-1432.|[2]Li L, et al. Determination of albendazole and metabolites in silkworm Bombyx mori hemolymph by ultrafast liquid chromatography tandem triple quadrupole mass spectrometry. PLoS One. 2014 Sep 25;9(9):e105637.|[3]Pourgholami MH, et al. In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole. Cancer Lett. 2001 Apr 10;165(1):43-9.|[4]Jung YY, et al. Regulation of apoptosis and autophagy by albendazole in human colon adenocarcinoma cells. Biochimie. 2022 Jul;198:155-166.|[5]Zhou F, et al. Albendazole inhibits HIF-1α-dependent glycolysis and VEGF expression in non-small cell lung cancer cells. Mol Cell Biochem. 2017 Apr;428(1-2):171-178.
- Research Area:
- Cancer; Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection;Apoptosis;Autophagy;Cell Cycle/DNA Damage;Cytoskeleton;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Protein Tyrosine Kinase/RTK
