Tizanidine
Product Sizes
10 mg
£ POA
HY-B0194-10MG
5 mg
£ POA
HY-B0194-5MG
50 mg
£ POA
HY-B0194-50MG
100 mg
£ POA
HY-B0194-100MG
About this Product
- SKU:
- HY-B0194
- Application:
- Electron Microscopy
- CAS Number:
- 51322-75-9
- Extra Details:
- Tizanidine; a skeletal muscle relaxant; is an orally effective central α2-adrenoceptor agonist (IC50 = 6.9 nmol). Tizanidine primarily exerts muscle relaxation effects by inhibiting the release of excitatory amino acids (glutamate and aspartate) from the presynaptic terminals of spinal cord interneurons. Tizanidine has anti-injury activity and can inhibit gastrointestinal (GI) transport. Tizanidine can inhibit the proliferation; migration; and invasion of lung cancer cells and induce cell apoptosis by upregulating Nischarin and inhibiting the AKT and Wnt3a/β-catenin signaling pathways. Tizanidine can be used to treat spasticity caused by diseases such as multiple sclerosis (MS); stroke; and spinal cord injury (SCI)[1][2][3][4].
- Molecular Weight:
- 253.71
- Purity:
- 99.58
- References:
- [1]Kamen L, et al. A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury. Curr Med Res Opin. 2008 Feb;24(2):425-39.
- Research Area:
- Cancer;Metabolic Disease;Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Neuronal Signaling
