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Proteins and Peptides

Bimatoprost

Product Sizes
50 mg
£ POA
HY-B0191-50MG
10 mg
£ POA
HY-B0191-10MG
100 mg
£ POA
HY-B0191-100MG
5 mg
£ POA
HY-B0191-5MG
25 mg
£ POA
HY-B0191-25MG
10mM/1mL
£ POA
HY-B0191-10MM
About this Product
SKU:
HY-B0191
Additional Names:
AGN 192024
CAS Number:
155206-00-1
Extra Details:
Bimatoprost is a prostaglandin analog that reduces intraocular pressure by regulating scleral and trabecular outflow. Bimatoprost is used in the study of open-angle glaucoma; ocular hypertension; and other forms of glaucoma. Topical application of bimatoprost induces fat atrophy and causes a deepening of the eyelid sulcus[1][2][3][4][5][6].
Molecular Weight:
415.57
Purity:
99.94
References:
[1]Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55(1):22-7.|[2]Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7.|[3]Stamer W D, et al. Proposed mechanism of long-term intraocular pressure lowering with the bimatoprost implant[J]. Investigative Ophthalmology & Visual Science, 2023, 64(3): 15-15.|[4]Patil A J, et al. Bimatoprost–a review[J]. Expert opinion on pharmacotherapy, 2009, 10(16): 2759-2768.|[5]Woodward, et al. "Bimatoprost: a novel antiglaucoma agent." Cardiovascular drug reviews 22.2 (2004): 103-120.|[6]Crowston, et al. "Effect of bimatoprost on intraocular pressure in prostaglandin FP receptor knockout mice." Investigative ophthalmology & visual science 46.12 (2005): 4571-4577.
Research Area:
Endocrinology; Cardiovascular Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C; 3 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
GPCR/G Protein;Metabolic Enzyme/Protease
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