Nafamostat
Product Sizes
100 mg
£ POA
HY-B0190-100MG
50 mg
£ POA
HY-B0190-50MG
25 mg
£ POA
HY-B0190-25MG
10 mg
£ POA
HY-B0190-10MG
5 mg
£ POA
HY-B0190-5MG
About this Product
- SKU:
- HY-B0190
- CAS Number:
- 81525-10-2
- Extra Details:
- Nafamostat; an anticoagulant; is a synthetic serine protease inhibitor. Nafamostat has anticancer and antivirus effect. Nafamostat induce apoptosis by up-regulating the expression of tumor necrosis factor receptor-1 (TNFR1). Nafamostat can be used in the development of the pathological thickening of the arterial wall[1][2][3][4].
- Molecular Weight:
- 347.37
- References:
- [1]Uwagawa T, et al. Mechanisms of synthetic serine protease inhibitor (FUT‐175)‐mediated cell death [J]. Cancer: Interdisciplinary International Journal of the American Cancer Society, 2007, 109(10): 2142-2153.|[2]Tajima H, et al. Enhanced invasiveness of pancreatic adenocarcinoma cells stably transfected with cationic trypsinogen cDNA [J]. International journal of cancer, 2001, 94(5): 699-704.|[3]Yan Y, et al. Nafamostat mesylate as a broad-spectrum candidate for the treatment of flavivirus infections by targeting envelope proteins [J]. Antiviral research, 2022, 202: 105325.|[4]Sawada M, et al. Prevention of neointimal formation by a serine protease inhibitor, FUT-175, after carotid balloon injury in rats [J]. Stroke, 1999, 30(3): 644-650.
- Research Area:
- Cancer; Infection
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
