Mosapride (citrate dihydrate)
Product Sizes
10 mg
£ POA
HY-B0189B-10MG
50 mg
£ POA
HY-B0189B-50MG
5 mg
£ POA
HY-B0189B-5MG
25 mg
£ POA
HY-B0189B-25MG
100 mg
£ POA
HY-B0189B-100MG
About this Product
- SKU:
- HY-B0189B
- Additional Names:
- TAK-370 (citrate dihydrate); AS-4370 (citrate dihydrate)
- Application:
- Electron Microscopy
- CAS Number:
- 636582-62-2
- Extra Details:
- Mosapride (TAK-370) citrate dehydrate is a gastroprokinetic agent with 5-hydroxytryptamine4 receptor agonist activity and has been widely used in the research of a variety of gastrointestinal disorders. Mosapride citrate dihydrate potently inhibits Kv4.3 in a concentration-dependent manner with IC50 values of 15.2 μM[1]. Mosapride citrate dihydrateselectively stimulates upper GI motility in vivo[2].
- Molecular Weight:
- 650.05
- Purity:
- 99.87
- References:
- [1]Sung KW, et al. Effect of mosapride on Kv4.3 potassium channels expressed in CHO cells. Naunyn-Schmiedeberg's archives of pharmacology. 2013;386(10):905-16.|[2]Mine Y, et al. Comparison of effect of mosapride citrate and existing 5-HT4 receptor agonists on gastrointestinal motility in vivo and in vitro. The Journal of pharmacology and experimental therapeutics. 1997;283(3):1000-8.
- Research Area:
- Metabolic Disease; Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
