Ellagic acid
Product Sizes
1 g
£ POA
HY-B0183-1G
5 g
£ POA
HY-B0183-5G
500 mg
£ POA
HY-B0183-500MG
100 mg
£ POA
HY-B0183-100MG
About this Product
- SKU:
- HY-B0183
- CAS Number:
- 476-66-4
- Extra Details:
- Ellagic acid is a natural antioxidant; and acts as a potent and ATP-competitive inhibitor of CK2 and SHP2; with an IC50 of 40 nM and a Ki of 20 nM.
- Molecular Weight:
- 302.19
- Purity:
- 99.75
- References:
- [1]Cozza G, et al. Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem. 2006 Apr 20;49(8):2363-6.|[2]Rizk HA, et al. Prophylactic effects of ellagic acid and rosmarinic acid on doxorubicin-induced neurotoxicity in rats. J Biochem Mol Toxicol. 2017 Dec;31(12).|[3]Ahire V, et al. Ellagic Acid Enhances Apoptotic Sensitivity of Breast Cancer Cells to γ-Radiation. Nutr Cancer. 2017 Aug-Sep;69(6):904-910.|[4]Ma CH, et al. Discovery of ellagic acid as a competitive inhibitor of Src homology phosphotyrosyl phosphatase 2 (SHP2) for cancer treatment: In vitro and in silico study. Int J Biol Macromol. 2023 Nov 5;254(Pt 2):127845.
- Research Area:
- Cancer; Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
