Olsalazine (Disodium)
Product Sizes
500 mg
£ POA
HY-B0174-500MG
1 g
£ POA
HY-B0174-1G
5 g
£ POA
HY-B0174-5G
10 g
£ POA
HY-B0174-10G
10mM/1mL
£ POA
HY-B0174-10MM
About this Product
- SKU:
- HY-B0174
- CAS Number:
- 6054-98-4
- Extra Details:
- Olsalazine Disodium is an orally active prodrug of 5-ASA (HY-15027). Olsalazine Disodium can inhibit cells proliferation and induce apoptosis. Olsalazine Disodium can reduce DAI and MPO activity and inhibit inflammatory cytokines levels. Olsalazine Disodium can be used for the researches of cancer; inflammation and metabolic disease; such as colorectal cancer; inflammatory bowel disease (IBD) and hyperuricemic[1][2][3][4].
- Molecular Weight:
- 346.20
- Purity:
- 99.89
- References:
- [1]Nielsen, O.H., H.W. Verspaget, and J. Elmgreen, Inhibition of intestinal macrophage chemotaxis to leukotriene B4 by sulphasalazine, olsalazine, and 5-aminosalicylic acid. Aliment Pharmacol Ther, 1988. 2(3): p. 203-11.|[2]Gionchetti, P., et al., Scavenger effect of sulfasalazine, 5-aminosalicylic acid, and olsalazine on superoxide radical generation. Dig Dis Sci, 1991. 36(2): p. 174-8.|[3]Brown, W.A., et al., 5-aminosalicyclic acid and olsalazine inhibit tumor growth in a rodent model of colorectal cancer. Dig Dis Sci, 2000. 45(8): p. 1578-84.
- Research Area:
- Cancer; Metabolic Disease; Inflammation/Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture and light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection;GPCR/G Protein
