L-Ascorbic acid
Product Sizes
10 g
£ POA
HY-B0166-10G
5 g
£ POA
HY-B0166-5G
1 g
£ POA
HY-B0166-1G
500 mg
£ POA
HY-B0166-500MG
50 g
£ POA
HY-B0166-50G
25 g
£ POA
HY-B0166-25G
10mM/1mL
£ POA
HY-B0166-10MM
About this Product
- SKU:
- HY-B0166
- Additional Names:
- L-Ascorbate; Vitamin C
- Application:
- Immunoprecipitation
- CAS Number:
- 50-81-7
- Extra Details:
- L-Ascorbic acid (L-Ascorbate); an electron donor; is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].
- Molecular Weight:
- 176.12
- Purity:
- 99.99
- References:
- [1]Sebastian J Padayatty, et al. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22(1):18-35.|[2]Michael T Nelson, et al. Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels by ascorbate. J Neurosci. 2007 Nov 14;27(46):12577-83.|[3]Aleksander Hinek, et al. Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin. J Dermatol Sci. 2014 Sep;75(3):173-82.|[4]Sungrae Cho, et al. Hormetic dose response to L-ascorbic acid as an anti-cancer drug in colorectal cancer cell lines according to SVCT-2 expression. Sci Rep. 2018 Jul 27;8(1):11372.|[5]Satyanarayana Sreemantula, et al. Influence of antioxidant (L- ascorbic acid) on tolbutamide induced hypoglycaemia/antihyperglycaemia in normal and diabetic rats. BMC Endocr Disord. 2005 Mar 3;5(1):2.
- Research Area:
- Cancer; Metabolic Disease; Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- RT; protect from light
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis;Immunology/Inflammation;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;NF-κB
