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Proteins and Peptides

Mizolastine

Product Sizes
500 mg
£ POA
HY-B0164-500MG
50 mg
£ POA
HY-B0164-50MG
25 mg
£ POA
HY-B0164-25MG
100 mg
£ POA
HY-B0164-100MG
10mM/1mL
£ POA
HY-B0164-10MM
About this Product
SKU:
HY-B0164
CAS Number:
108612-45-9
Extra Details:
Mizolastine is an orally active; high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine effectively inhibits mRNA expression of VEGF165; VEGF120; TNF-α and KC. Mizolastine can be used in studies of allergic rhinitis and chronic idiopathic urticarial[1][2][3].
Molecular Weight:
432.49
Purity:
99.82
References:
[1]Xia Q, et al. The effect of mizolastine on expression of vascular endothelial cell growth factor, tumour necrosis factor-alpha and keratinocyte-derived chemokine in murine mast cells, compared with dexamethasone and loratadine. Clin Exp Dermatol. 2005 Mar;30(2):165-70. |[2]Ren X, et al. The anti-inflammatory effects of Yunnan Baiyao are involved in regulation of the phospholipase A2/arachidonic acid metabolites pathways in acute inflammation rat model. Mol Med Rep. 2017 Oct;16(4):4045-4053.|[3]Prakash A, et al. Mizolastine: a review of its use in allergic rhinitis and chronic idiopathic urticaria. BioDrugs. 1998 Jul;10(1):41-63.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
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