Lafutidine
Product Sizes
50 mg
£ POA
HY-B0160-50MG
100 mg
£ POA
HY-B0160-100MG
500 mg
£ POA
HY-B0160-500MG
250 mg
£ POA
HY-B0160-250MG
10mM/1mL
£ POA
HY-B0160-10MM
1 g
£ POA
HY-B0160-1G
About this Product
- SKU:
- HY-B0160
- Additional Names:
- FRG-8813
- CAS Number:
- 118288-08-7
- Extra Details:
- Lafutidine (FRG-8813) is a histamine H2-receptor antagonist (H2RA); with proven gastric mucosal protective effects. Lafutidine can be used for the research of gastroesophageal reflux disease[1].
- Molecular Weight:
- 431.55
- Purity:
- 99.56
- References:
- [1]Motoko Nakano, et al. Possible involvement of host defense mechanism in the suppression of rat acute reflux esophagitis by the particular histamine H2 receptor antagonist lafutidine. Pharmacology. 2012;90(3-4):205-11.|[2]Tetsuhiro Sugiyama, et al. Lafutidine facilitates calcitonin gene-related peptide (CGRP) nerve-mediated vasodilation via vanilloid-1 receptors in rat mesenteric resistance arteries. J Pharmacol Sci. 2008 Mar;106(3):505-11.|[3]Mitsuaki Okayama, et al. Protective effect of lafutidine, a novel histamine H2-receptor antagonist, on dextran sulfate sodium-induced colonic inflammation through capsaicin-sensitive afferent neurons in rats. Dig Dis Sci. 2004 Oct;49(10):1696-704.
- Research Area:
- Metabolic Disease; Endocrinology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
