Flucytosine
Product Sizes
1 g
£ POA
HY-B0139-1G
5 g
£ POA
HY-B0139-5G
500 mg
£ POA
HY-B0139-500MG
10mM/1mL
£ POA
HY-B0139-10MM
About this Product
- SKU:
- HY-B0139
- Additional Names:
- 5-Fluorocytosine; NSC 103805; Ro 2-9915
- CAS Number:
- 2022-85-7
- Extra Details:
- Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that; after further metabolism; produces fluorinated ribonucleotides and deoxyribonucleotides; inhibits DNA and protein synthesis; and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells[1][2][3].
- Molecular Weight:
- 129.09
- Purity:
- 99.99
- References:
- [1]Vermes A, et al. Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions. J Antimicrob Chemother. 2000 Aug;46(2):171-9.|[2]You MH, et al. Cytosine deaminase-producing human mesenchymal stem cells mediate an antitumor effect in a mouse xenograft model. J Gastroenterol Hepatol. 2009 Aug;24(8):1393-400.|[3]Iovannitti C, et al. Itraconazole and flucytosine+itraconazole combination in the treatment of experimental cryptococcosis in hamsters. Mycoses. 1995 Nov-Dec;38(11-12):449-52.
- Research Area:
- Infection; Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection
