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Proteins and Peptides

Bestatin

Product Sizes
100 mg
£ POA
HY-B0134-100MG
25 mg
£ POA
HY-B0134-25MG
10 mg
£ POA
HY-B0134-10MG
5 mg
£ POA
HY-B0134-5MG
50 mg
£ POA
HY-B0134-50MG
10mM/1mL
£ POA
HY-B0134-10MM
About this Product
SKU:
HY-B0134
Additional Names:
Ubenimex
CAS Number:
58970-76-6
Extra Details:
Bestatin is a natural; broad-spectrum; and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects[1][2].
Molecular Weight:
308.37
Purity:
99.98
References:
[1]Hossain A, et al. Protective effects of bestatin in the retina of streptozotocin-induced diabetic mice. Exp Eye Res. 2016 Aug;149:100-6|[2]Qian X, et al. Inhibition of p38 MAPK Phosphorylation Is Critical for Bestatin to Enhance ATRA-Induced Cell Differentiation in Acute Promyelocytic Leukemia NB4 Cells. Am J Ther. 2016 May-Jun;23(3):e680-9.|[3]Lis M, et al. The effects of bestatin on humoral response to sheep erythrocytes in non-treated and cyclophosphamide-immunocompromised mice. Immunopharmacol Immunotoxicol. 2013 Feb;35(1):133-8|[4]Poloz Y, et al. Bestatin inhibits cell growth, cell division, and spore cell differentiation in Dictyostelium discoideum. Eukaryot Cell. 2012 Apr;11(4):545-57
Research Area:
Cancer; Infection
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Anti-infection;Metabolic Enzyme/Protease
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