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Proteins and Peptides

Prostaglandin E1

Product Sizes
10 mg
£ POA
HY-B0131-10MG
1 mg
£ POA
HY-B0131-1MG
5 mg
£ POA
HY-B0131-5MG
50 mg
£ POA
HY-B0131-50MG
25 mg
£ POA
HY-B0131-25MG
100 mg
£ POA
HY-B0131-100MG
About this Product
SKU:
HY-B0131
Additional Names:
Alprostadil; PGE1
Application:
Electron Microscopy
CAS Number:
745-65-3
Extra Details:
Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand; with Kis of 1.1 nM; 2.1 nM; 10 nM; 33 nM and 36 nM for mouse EP3; EP4; EP2; IP and EP1; respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases[1][2][3].
Molecular Weight:
354.48
Purity:
99.76
References:
[1]Kiriyama M, et, al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol. 1997 Sep;122(2):217-24.|[2]Cattaneo MG, et, al. Alprostadil suppresses angiogenesis in vitro and in vivo in the murine Matrigel plug assay. Br J Pharmacol. 2003 Jan;138(2):377-85.|[3]Hauck EW, et, al. Prostaglandin E1 long-term self-injection programme for treatment of erectile dysfunction--a follow-up of at least 5 years. Andrologia. 1999;31 Suppl 1:99-103.
Research Area:
Endocrinology; Cardiovascular Disease; Cancer
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; stored under nitrogen)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
GPCR/G Protein;Metabolic Enzyme/Protease
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