Zonisamide-d4
Product Sizes
5 mg
£ POA
HY-B0124S-5MG
1 mg
£ POA
HY-B0124S-1MG
About this Product
- SKU:
- HY-B0124S
- CAS Number:
- 1020720-04-0
- Extra Details:
- Zonisamide-d4 is the deuterium labeled Zonisamide. Zonisamide (AD 810) is an inhibitor of zinc enzyme carbonic anhydrase (CA); with Kis of 35.2 nM and 20.6 nM for human mitochondrial isozyme hCA II and hCA V; respectively. Zonisamide has antiepileptic activity. Zonisamide can be used for the rsearch for epilepsy; seizures and Parkinson's disease[1][2].
- Molecular Weight:
- 216.25
- Purity:
- 99.38
- References:
- [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Peters DH, et al. Zonisamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy. Drugs. 1993 May;45(5):760-87.|[3]De Simone G, et al. Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies. Bioorg Med Chem Lett. 2005 May 2;15(9):2315-20.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture and light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;Others
