Sumatriptan succinate
Product Sizes
50 mg
£ POA
HY-B0121-50MG
100 mg
£ POA
HY-B0121-100MG
500 mg
£ POA
HY-B0121-500MG
25 mg
£ POA
HY-B0121-25MG
10 mg
£ POA
HY-B0121-10MG
10mM/1mL
£ POA
HY-B0121-10MM
About this Product
- SKU:
- HY-B0121
- Additional Names:
- GR 43175 succinate
- CAS Number:
- 103628-48-4
- Extra Details:
- Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nm; 9.3nm and 17.8 nm for 5-HT1D; 5-HT1B and 5-HT1F receptors; respectively. Sumatriptan succinate can be used for migraine headache research[1][2][3][4].
- Molecular Weight:
- 413.49
- Purity:
- 99.89
- References:
- [1]S J Peroutka, et al. Sumatriptan (GR 43175) interacts selectively with 5-HT1B and 5-HT1D binding sites. Eur J Pharmacol. 1989 Apr 12;163(1):133-6. |[2]K L Dechant, et al. Sumatriptan. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the acute treatment of migraine and cluster headache. Drugs. 1992 May;43(5):776-98. |[3]Razzaque Z, et al. Vasoconstriction in human isolated middle meningeal arteries: determining the contribution of 5-HT1B- and 5-HT1F-receptor activation. Br J Clin Pharmacol. 1999 Jan;47(1):75-82.|[4]Bates EA, et al. Sumatriptan alleviates nitroglycerin-induced mechanical and thermal allodynia in mice. Cephalalgia. 2010 Feb;30(2):170-8.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Neuronal Signaling
