Risedronic acid (sodium)
Product Sizes
1 g
£ POA
HY-B0119-1G
500 mg
£ POA
HY-B0119-500MG
100 mg
£ POA
HY-B0119-100MG
10mM/1mL
£ POA
HY-B0119-10MM
About this Product
- SKU:
- HY-B0119
- Additional Names:
- Risedronate (sodium)
- CAS Number:
- 115436-72-1
- Extra Details:
- Risedronic acid (Risedronate) sodium; a bisphosphonate; is a potent anti-resorption agent that inhibits osteoclast-mediated bone resorption and changes the bone metabolism. Risedronic acid sodium suppresses osteoblast differentiation and induced caspase- and isoprenoid depletion-dependent apoptosis. Risedronic acid sodium inhibits blood stages of Plasmodium falciparum (IC50 of 20.3 μM). Risedronic acid sodium inhibits the transfer of the farnesyl pyrophosphate group to parasite proteins[1][2][3].
- Molecular Weight:
- 305.09
- Purity:
- 99.72
- References:
- [1]Fujita H, et al. Effect of risedronate on osteoblast differentiation, expression of receptor activator of NF-κB ligand and apoptosis in mesenchymal stem cells. Basic Clin Pharmacol Toxicol. 2011 Aug;109(2):78-84. |[2]Jordao FM, et al. In vitro and in vivo antiplasmodial activities of risedronate and its interference with protein prenylation in Plasmodium falciparum. Antimicrob Agents Chemother. 2011 May;55(5):2026-31.|[3]Willey JS, et al. Risedronate prevents early radiation-induced osteoporosis in mice at multiple skeletal locations. Bone. 2010 Jan;46(1):101-11.
- Research Area:
- Cancer; Infection; Metabolic Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection;Apoptosis
