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Proteins and Peptides

(+)-Ketoconazole

Product Sizes
5 mg
£ POA
HY-B0105A-5MG
25 mg
£ POA
HY-B0105A-25MG
50 mg
£ POA
HY-B0105A-50MG
10 mg
£ POA
HY-B0105A-10MG
100 mg
£ POA
HY-B0105A-100MG
10mM/1mL
£ POA
HY-B0105A-10MM
About this Product
SKU:
HY-B0105A
Additional Names:
(+)-Ketoconazol; (+)-R 41400
CAS Number:
142128-59-4
Extra Details:
(+)-Ketoconazole ((+)-Ketoconazol; (+)-R 41400) is the (+)-(2R;4S) enantiomer of Ketoconazole (HY-B0105). Ketoconazole is an imidazole antifungal agent; which is usually administered as a racemate ((±)-Ketoconazole; a mixture of equal amounts of (+) and (-) enantiomers). Compared with the (-)-Ketoconazole enantiomer; (+)-Ketoconazole shows higher plasma concentration; lower clearance rate and smaller volume of distribution[1].
Molecular Weight:
531.43
Purity:
99.79
References:
[1]Eil C. Ketoconazole binds to the human androgen receptor. Horm Metab Res. 1992 Aug;24(8):367-70.|[2]Seif El-Din SH, et al. Effect of ketoconazole, a cytochrome P450 inhibitor, on the efficacy of quinine and halofantrine against Schistosoma mansoni in mice. Korean J Parasitol. 2013 Apr;51(2):165-75.
Research Area:
Infection
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Anti-infection;Metabolic Enzyme/Protease
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