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Proteins and Peptides

Benazepril

Product Sizes
100 mg
£ POA
HY-B0093-100MG
25 mg
£ POA
HY-B0093-25MG
50 mg
£ POA
HY-B0093-50MG
10 mg
£ POA
HY-B0093-10MG
10mM/1mL
£ POA
HY-B0093-10MM
About this Product
SKU:
HY-B0093
Additional Names:
CGS14824A (free base)
CAS Number:
86541-75-5
Extra Details:
Benazepril (CGS14824A free base) is an orally active angiotensin-converting enzyme (ACE) inhibitor to reduce angiotensin-II production. Benazepril inhibits oxidative stress and inhibits apoptosis by the PI3K/Akt signaling pathway. Benazepril improves diabetic nephropathy and decreases proteinuria. Benazepril can be used in the study of hypertension; heart failure and diabetic nephropathy[1][2].
Molecular Weight:
424.49
Purity:
99.85
References:
[1]Hou FF, et al. Efficacy and safety of benazepril for advanced chronic renal insufficiency. N Engl J Med. 2006 Jan 12;354(2):131-40.|[2]Huang XM, et al. Effects of chronotherapy of benazepril on the diurnal profile of RAAS and clock genes in the kidney of 5/6 nephrectomy rats. J Huazhong Univ Sci Technolog Med Sci. 2013 Jun;33(3):368-74.
Research Area:
Cardiovascular Disease; Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
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