Acarbose
Product Sizes
200 mg
£ POA
HY-B0089-200MG
1 g
£ POA
HY-B0089-1G
10mM/1mL
£ POA
HY-B0089-10MM
About this Product
- SKU:
- HY-B0089
- Additional Names:
- BAY g 5421
- Application:
- Immunoprecipitation
- CAS Number:
- 56180-94-0
- Extra Details:
- Acarbose (BAY g 5421); antihyperglycemic agent; is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin[1][2][3].
- Molecular Weight:
- 645.60
- Purity:
- 99.97
- References:
- [1]Zhang Q, et al. Acarbose Reduces Blood Glucose by Activating miR-10a-5p and miR-664 in Diabetic Rats. PLoS One. 2013 Nov 18;8(11):e79697.|[2]Chan KC, et al. Pleiotropic effects of acarbose on atherosclerosis development in rabbits are mediated via upregulating AMPK signals. Sci Rep. 2016 Dec 7;6:3864|[3]Hanefeld M, et al. Acarbose: oral anti-diabetes drug with additional cardiovascular benefits [published correction appears in Expert Rev Cardiovasc Ther. 2009 Mar;7(3):330]. Expert Rev Cardiovasc Ther. 2008;6(2):153-163.|[4]Yee HS, et al. A review of the safety and efficacy of acarbose in diabetes mellitus. Pharmacotherapy. 1996;16(5):792-805.|[5]Oki T, et al. Evaluation of alpha-glucosidase inhibition by using an immobilized assay system. Biol Pharm Bull. 2000;23(9):1084-1087.
- Research Area:
- Cancer;Infection;Metabolic Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
