Azelnidipine
Product Sizes
10 mg
£ POA
HY-B0023-10MG
100 mg
£ POA
HY-B0023-100MG
50 mg
£ POA
HY-B0023-50MG
5 mg
£ POA
HY-B0023-5MG
25 mg
£ POA
HY-B0023-25MG
10mM/1mL
£ POA
HY-B0023-10MM
About this Product
- SKU:
- HY-B0023
- Additional Names:
- CS 905
- CAS Number:
- 123524-52-7
- Extra Details:
- Azelnidipine (CS 905) is a dihydropyridine calcium channel blocker that is effective orally. Azelnidipine inhibits the intracellular calcium ion flow and lower blood pressure by selectively blocking L-type calcium channel on the membrane of vascular smooth muscle. Azelnidipine inhibits esophageal squamous cell carcinoma proliferation by targeting MEK1/2. Azelnidipine also has anti-inflammatory; antioxidant and neuroprotective effects [1] [2] [3].
- Molecular Weight:
- 582.65
- Purity:
- 99.79
- References:
- [1]Ram CVS. Therapeutic Usefulness of a Novel Calcium Channel Blocker Azelnidipine in the Treatment of Hypertension: A Narrative Review. Cardiol Ther. 2022 Dec;11(4):473-489.|[2]Zhao L, et al. Azelnidipine inhibits esophageal squamous cell carcinoma proliferation in vivo and in vitro by targeting MEK1/2. Mol Ther Oncolytics. 2022 Sep 26;27:61-72.|[3]Fakharaldeen Z, et al. Potential protective effects of Azelnidipine against cerebral ischemia-reperfusion injury in male rats. J Med Life. 2022 Nov;15(11):1384-1391.|[4]Oizumi K, et al. Antihypertensive effects of CS-905, a novel dihydropyridine Ca <sup>++</sup> channel blocker. Jpn J Pharmacol. 1989 Sep;51(1):57-64.
- Research Area:
- Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- MAPK/ERK Pathway;Membrane Transporter/Ion Channel;Neuronal Signaling
