Carvedilol (phosphate hemihydrate)
Product Sizes
25 mg
£ POA
HY-B0006A-25MG
100 mg
£ POA
HY-B0006A-100MG
50 mg
£ POA
HY-B0006A-50MG
500 mg
£ POA
HY-B0006A-500MG
1 g
£ POA
HY-B0006A-1G
250 mg
£ POA
HY-B0006A-250MG
10mM/1mL
£ POA
HY-B0006A-10MM
About this Product
- SKU:
- HY-B0006A
- Additional Names:
- BM 14190 (phosphate hemihydrate)
- Application:
- Antibody Microarray
- CAS Number:
- 610309-89-2
- Extra Details:
- Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is a non-selective β/α-1 blocker[1]. Carvedilol phosphate hemihydrate inhibits lipid peroxidation with an IC50 of 5 μM. Carvedilol phosphate hemihydrate is a multiple action antihypertensive agent with potential use in angina and congestive heart failure[2]. Carvedilol phosphate hemihydrate is an autophagy inducer that inhibits the NLRP3 inflammasome[3].
- Molecular Weight:
- 513.48
- Purity:
- 99.94
- References:
- [1]Eggertsen R, et al. Acute haemodynamic effects of carvedilol (BM 14190), a new combined beta-adrenoceptor blocker and precapillary vasodilating agent, in hypertensive patients. Eur J Clin Pharmacol. 1984;27(1):19-22.|[2]Feuerstein GZ, et al. Myocardial protection by the novel vasodilating beta-blocker, carvedilol: potential relevance of anti-oxidant activity. J Hypertens Suppl. 1993 Jun;11(4):S41-8.|[3]Wong WT, et al. Repositioning of the β-Blocker Carvedilol as a Novel Autophagy Inducer That Inhibits the NLRP3 Inflammasome. Front Immunol. 2018 Aug 22;9:1920.
- Research Area:
- Cancer; Inflammation/Immunology; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection;Autophagy;GPCR/G Protein;Neuronal Signaling
