(Rac)-Bepotastine (besilate)
Product Sizes
10 mg
£ POA
HY-A0015A-10MG
50 mg
£ POA
HY-A0015A-50MG
25 mg
£ POA
HY-A0015A-25MG
5 mg
£ POA
HY-A0015A-5MG
10mM/1mL
£ POA
HY-A0015A-10MM
About this Product
- SKU:
- HY-A0015A
- Application:
- Electron Microscopy
- CAS Number:
- 1415692-17-9
- Extra Details:
- (Rac)-Bepotastine (besilate) is the isomer of Bepotastine (besilate) (HY-A0015); and can be used as an experimental control. Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist; can suppress the expression of nerve growth factor (NGF). Bepotastine besilate has the potential for allergic rhinitis; allergic conjunctivitis and urticaria/pruritus research[1][2][3][4].
- Molecular Weight:
- 547.06
- Purity:
- 99.52
- References:
- [1]Kida T, et al. Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models. Exp Eye Res. 2010 Jul;91(1):85-91.|[2]Kamata Y, et al. Bepotastine besilate downregulates the expression of nerve elongation factors in normal human epidermal keratinocytes. J Dermatol Sci. 2018 Apr 23:S0923-1811(18)30186-5.|[3]Tanizaki H, et al. Oral administration of bepotastine besilate suppressed scratching behavior of atopic dermatitis model NC/Nga mice. Int Arch Allergy Immunol. 2008;145(4):277-82.|[4]Jon I Williams, et al. Non-clinical pharmacology, pharmacokinetics, and safety findings for the antihistamine bepotastine besilate. Curr Med Res Opin. 2010 Oct;26(10):2329-38.
- Research Area:
- Endocrinology; Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
