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Proteins and Peptides

(2S;4S)-Sacubitril

Product Sizes
1 mg
£ POA
HY-78841-1MG
5 mg
£ POA
HY-78841-5MG
About this Product
SKU:
HY-78841
CAS Number:
149709-63-7
Extra Details:
(2S;4S)-Sacubitril is the impurity of Sacubitril. Sacubitril is a potent NEP inhibitor that can be used for the research of heart failure[1][2].
Molecular Weight:
411.49
Purity:
98.33
References:
[1]Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9.|[2]Halama A, et, al. Synthesis, Isolation, and Analysis of Stereoisomers of Sacubitril. Org. Process Res. Dev. 2019, 23, 1, 102-107.
Research Area:
Cardiovascular Disease
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Metabolic Enzyme/Protease
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