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Proteins and Peptides

(S)-(+)-Ibuprofen (Standard)

Product Sizes
250 mg
£ POA
HY-78131AR-250MG
100 mg
£ POA
HY-78131AR-100MG
50 mg
£ POA
HY-78131AR-50MG
25 mg
£ POA
HY-78131AR-25MG
About this Product
SKU:
HY-78131AR
Additional Names:
Dexibuprofen (Standard)
CAS Number:
51146-56-6
Extra Details:
(S)-(+)-Ibuprofen (Standard) is the analytical standard of (S)-(+)-Ibuprofen. This product is intended for research and analytical applications. (S)-(+)-Ibuprofen ((S)-Ibuprofen); a S(+)-enantiomer of Ibuprofen; is a potent COX-1 and COX-2 inhibitor with IC50s of 2.1 μM and 1.6 μM; respectively. (S)-(+)-Ibuprofen has analgesic; anti-inflammatory; anticancer and antipyretic effects[1][2].
Molecular Weight:
206.28
Purity:
99.87
References:
[1]Evans AM, et al. Comparative pharmacology of S(+)-ibuprofen and (RS)-ibuprofen. Clin Rheumatol. 2001 Nov;20 Suppl 1:S9-14.|[2]N Scheuren, et al. Modulation of transcription factor NF-kappaB by enantiomers of the nonsteroidal drug ibuprofen. Br J Pharmacol. 1998 Feb;123(4):645-52.|[3]Astrid Janssen, et al. Evidence of COX-2 independent induction of apoptosis and cell cycle block in human colon carcinoma cells after S- or R-ibuprofen treatment. Eur J Pharmacol. 2006 Jul 1;540(1-3):24-33.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C; sealed storage; away from light and moisture
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Immunology/Inflammation
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