(S)-(+)-Ibuprofen
Product Sizes
1 g
£ POA
HY-78131A-1G
5 g
£ POA
HY-78131A-5G
10mM/1mL
£ POA
HY-78131A-10MM
10 g
£ POA
HY-78131A-10G
25 g
£ POA
HY-78131A-25G
100 g
£ POA
HY-78131A-100G
About this Product
- SKU:
- HY-78131A
- Additional Names:
- Dexibuprofen
- CAS Number:
- 51146-56-6
- Extra Details:
- (S)-(+)-Ibuprofen ((S)-Ibuprofen); a S(+)-enantiomer of Ibuprofen; is a potent COX-1 and COX-2 inhibitor with IC50s of 2.1 μM and 1.6 μM; respectively. (S)-(+)-Ibuprofen has analgesic; anti-inflammatory; anticancer and antipyretic effects[1][2].
- Molecular Weight:
- 206.28
- Purity:
- 99.99
- References:
- [1]Evans AM, et al. Comparative pharmacology of S(+)-ibuprofen and (RS)-ibuprofen. Clin Rheumatol. 2001 Nov;20 Suppl 1:S9-14.|[2]N Scheuren, et al. Modulation of transcription factor NF-kappaB by enantiomers of the nonsteroidal drug ibuprofen. Br J Pharmacol. 1998 Feb;123(4):645-52.|[3]Astrid Janssen, et al. Evidence of COX-2 independent induction of apoptosis and cell cycle block in human colon carcinoma cells after S- or R-ibuprofen treatment. Eur J Pharmacol. 2006 Jul 1;540(1-3):24-33.
- Research Area:
- Inflammation/Immunology; Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Immunology/Inflammation
