(Rac)-Roscovitine
Product Sizes
1 g
£ POA
HY-50892-1G
25 mg
£ POA
HY-50892-25MG
250 mg
£ POA
HY-50892-250MG
50 mg
£ POA
HY-50892-50MG
100 mg
£ POA
HY-50892-100MG
About this Product
- SKU:
- HY-50892
- Additional Names:
- (Rac)-Seliciclib; (Rac)-CYC202
- CAS Number:
- 186692-44-4
- Extra Details:
- (Rac)-Roscovitine ((Rac)-Seliciclib) is a selective cyclin-dependent kinases (CDKs) inhibitor. (Rac)-Roscovitine binds to the active sites of CDKs competitively with ATP; inhibiting the phosphorylation activity of CDKs. (Rac)-Roscovitine induces apoptosis in cancer cells. (Rac)-Roscovitine is promising for research of cancers or other diseases associated with CDK dysregulation; such as neurodegenerative diseases; cardiac disorders; viral and protozoan infections; glomerulonephritis; and chronic inflammation[1].
- Molecular Weight:
- 354.45
- References:
- [1]Jorda R, et al. Pyrazolo[4,3-d]pyrimidine bioisostere of roscovitine: evaluation of a novel selective inhibitor of cyclin-dependent kinases with antiproliferative activity. J Med Chem. 2011 Apr 28;54(8):2980-93.
- Research Area:
- Cancer; Infection; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
