GW-1100
Product Sizes
50 mg
£ POA
HY-50691-50MG
10 mg
£ POA
HY-50691-10MG
5 mg
£ POA
HY-50691-5MG
10mM/1mL
£ POA
HY-50691-10MM
25 mg
£ POA
HY-50691-25MG
About this Product
- SKU:
- HY-50691
- Application:
- Immunoprecipitation
- CAS Number:
- 306974-70-9
- Extra Details:
- GW-1100 is a selective GPR40 antagonist with a pIC50 of 6.9.
- Molecular Weight:
- 520.58
- Purity:
- 97.14
- References:
- [1]Stoddart LA, et al. Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5'-O-(3-[35S]thio)triphosphate binding studies reflects binding of an endogenous agonist. Mol Pharmacol. 2007 Apr;71(|[2]Briscoe CP, et al. Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules. Br J Pharmacol. 2006 Jul;148(5):619-28.|[3]Manosalva C, et al. Cloning, identification and functional characterization of bovine free fatty acid receptor-1 (FFAR1/GPR40) in neutrophils. PLoS One. 2015 Mar 19;10(3):e0119715.|[4]Nakamoto K, et al. Hypothalamic GPR40 signaling activated by free long chain fatty acids suppresses CFA-induced inflammatorychronic pain. PLoS One. 2013 Dec 12;8(12):e81563.
- Research Area:
- Metabolic Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein
