Azido-PEG4-CH2-Boc
Product Sizes
1 g
£ POA
HY-42618-1G
500 mg
£ POA
HY-42618-500MG
250 mg
£ POA
HY-42618-250MG
100 mg
£ POA
HY-42618-100MG
5 g
£ POA
HY-42618-5G
10 g
£ POA
HY-42618-10G
25 g
£ POA
HY-42618-25G
About this Product
- SKU:
- HY-42618
- Application:
- Antibody Microarray
- CAS Number:
- 864681-04-9
- Extra Details:
- Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG4-CH2-Boc is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 333.38
- Purity:
- 97.0
- References:
- [1]Shiladitya Sengupta, et al. Targeted drug delivery through affinity based linkers. WO2015148126A1.|[2]Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;PROTAC
