(rac)-Exatecan Intermediate 1
Product Sizes
50 mg
£ POA
HY-42487A-50MG
1 g
£ POA
HY-42487A-1G
100 mg
£ POA
HY-42487A-100MG
25 mg
£ POA
HY-42487A-25MG
250 mg
£ POA
HY-42487A-250MG
10mM/1mL
£ POA
HY-42487A-10MM
About this Product
- SKU:
- HY-42487A
- CAS Number:
- 102978-40-5
- Extra Details:
- (rac)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631); a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian; lung and breast cancer[1][2].
- Molecular Weight:
- 263.25
- Purity:
- 99.97
- References:
- [1]Weng W, et al. Antibody-Exatecan Conjugates with a Novel Self-immolative Moiety Overcome Resistance in Colon and Lung Cancer. Cancer Discov. 2023 Apr 3;13(4):950-973.|[2]Zhang Hongwei, et al. Intermediate for synthesizing camptothecin derivatives using exatecan mesylate and its preparation method and application. China, CN111470998. 2020-07-31.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
