1-Methylisatin
Product Sizes
1 g
£ POA
HY-23148-1G
5 g
£ POA
HY-23148-5G
10 g
£ POA
HY-23148-10G
10mM/1mL
£ POA
HY-23148-10MM
About this Product
- SKU:
- HY-23148
- Additional Names:
- N-Methylisatin
- CAS Number:
- 2058-74-4
- Extra Details:
- 1-Methylisatin is a potent and selective CE (carboxylesterases) inhibitor; with Kis of 38.2 and 5.38 μM for hiCE and hCE1; respectively. 1-Methylisatin interacts with Hb (human adult hemoglobin) by hydrophobic binding and electrostatic attraction. 1-Methylisatin can be used in the study of regulation of agent metabolism in vivo[1][2].
- Molecular Weight:
- 161.16
- Purity:
- 99.81
- References:
- [1]Hyatt JL, et al. Selective inhibition of carboxylesterases by isatins, indole-2,3-diones. J Med Chem. 2007 Apr 19;50(8):1876-85.|[2]Mandal P, et al. Fluorescence spectroscopic characterization of the interaction of human adult hemoglobin and two isatins, 1-methylisatin and 1-phenylisatin: a comparative study. J Phys Chem B. 2009 Nov 12;113(45):14904-13.
- Research Area:
- Others
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
