BMS-1
Product Sizes
25 mg
£ POA
HY-19991-25MG
50 mg
£ POA
HY-19991-50MG
100 mg
£ POA
HY-19991-100MG
5 mg
£ POA
HY-19991-5MG
10 mg
£ POA
HY-19991-10MG
10mM/1mL
£ POA
HY-19991-10MM
About this Product
- SKU:
- HY-19991
- Additional Names:
- PD-1/PD-L1 inhibitor 1
- Application:
- Antibody Microarray
- CAS Number:
- 1675201-83-8
- Extra Details:
- BMS-1 is an inhibitor of the PD-1/PD-L1 protein/protein interaction (IC50 between 6 and 100 nM)[1][2].
- Molecular Weight:
- 475.58
- Purity:
- 99.89
- References:
- [1]Zhao Y, et al. Depression Promotes Hepatocellular Carcinoma Progression through a Glucocorticoids Mediated Up-Regulation of PD-1 Expression in Tumor infiltrating NK Cells. Carcinogenesis. 2019 Feb 4.|[2]Li K, et al. Development of small-molecule immune checkpoint inhibitors of PD-1/PD-L1 as a new therapeutic strategy for tumour immunotherapy. J Drug Target. 2019 Mar;27(3):244-256.|[3]Zhang H, et al. Utilizing VEGF165b mutant as an effective immunization adjunct to augment antitumor immune response. Vaccine. 2019 Apr 3;37(15):2090-2098.|[4]Mengyuan Li, et al. KALRN mutations promote antitumor immunity and immunotherapy response in cancer. J Immunother Cancer. 2020 Oct;8(2):e000293.
- Research Area:
- Cancer; Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis;Immunology/Inflammation
