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Proteins and Peptides

(Rac)-NSC305787 (hydrochloride)

Product Sizes
50 mg
£ POA
HY-18931A-50MG
100 mg
£ POA
HY-18931A-100MG
10 mg
£ POA
HY-18931A-10MG
5 mg
£ POA
HY-18931A-5MG
10mM/1mL
£ POA
HY-18931A-10MM
About this Product
SKU:
HY-18931A
CAS Number:
53868-26-1
Extra Details:
NSC305787 hydrochloride is an inhibitor of ezrin with a Kd of 5.85 μM; inhibits the phosphorylation of ezrin caused by PKCΙ with an IC50 of 8.3 μM; has antitumor activity.
Molecular Weight:
481.89
Purity:
98.18
References:
[1]Bulut G, et al. Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells. Oncogene. 2012 Jan 19;31(3):269-81.|[2]Çelik H, et al. Ezrin Inhibition Up-regulates Stress Response Gene Expression. J Biol Chem. 2016 Jun 17;291(25):13257-70.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
4[o]C (Powder; sealed storage; away from moisture)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Cytoskeleton
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