(Rac)-NSC305787
Product Sizes
50 mg
£ POA
HY-18931-50MG
10 mg
£ POA
HY-18931-10MG
5 mg
£ POA
HY-18931-5MG
100 mg
£ POA
HY-18931-100MG
10mM/1mL
£ POA
HY-18931-10MM
About this Product
- SKU:
- HY-18931
- CAS Number:
- 785718-37-8
- Extra Details:
- NSC305787 is an inhibitor of ezrin with a Kd of 5.85 μM; inhibits the phosphorylation of ezrin caused by PKCΙ with an IC50 of 8.3 μM; has antitumor activity.
- Molecular Weight:
- 445.42
- Purity:
- 99.29
- References:
- [1]Bulut G, et al. Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells. Oncogene. 2012 Jan 19;31(3):269-81.|[2]Çelik H, et al. Ezrin Inhibition Up-regulates Stress Response Gene Expression. J Biol Chem. 2016 Jun 17;291(25):13257-70.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cytoskeleton
