AMG-172
Product Sizes
25 mg
£ POA
HY-185483-25MG
10 mg
£ POA
HY-185483-10MG
5 mg
£ POA
HY-185483-5MG
1 mg
£ POA
HY-185483-1MG
About this Product
- SKU:
- HY-185483
- Extra Details:
- AMG-172 is an antibody-drug conjugate (ADC) composed of a fully human IgG1 monoclonal anti-CD27L antibody conjugated to DM1 via the non-cleavable linker MCC. AMG-172 releases the intracellular active component Lysine-MCC-DM through catabolism. Lysine-MCC-DM inhibits the assembly and disassembly dynamics of Microtubule and induces cell arrest at metaphase. AMG-172 can be used for research on relapsed/refractory clear cell renal cell carcinoma[1].
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
