3'-O-(2-Nitrobenzyl)-dTTP
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HY-185274-1EACH
About this Product
- SKU:
- HY-185274
- CAS Number:
- 219607-49-5
- Extra Details:
- 3'-O-(2-Nitrobenzyl)-dTTP acts as a reversible terminator for DNA chain elongation. 3'-O-(2-Nitrobenzyl)-dTTP interacts with 9°N polymerase (exo-) A485L/Y409V; gets recognized and incorporated into the elongating DNA chain; thereby temporarily terminating the polymerase reaction. 3'-O-(2-Nitrobenzyl)-dTTP carries a 3'-O-(2-nitrobenzyl) blocking group; which can be removed by laser irradiation to regenerate the free 3'-OH− group and restore polymerase activity. 3'-O-(2-Nitrobenzyl)-dTTP is applicable in DNA sequencing studies[1].
- Molecular Weight:
- 617.29
- Research Area:
- Others
- Shipping Conditions:
- Ambient
- Type:
- Molecular Biology Reagents: Nucleic Acids
