BSJ-05-037
Product Sizes
10 mg
£ POA
HY-185206-10MG
5 mg
£ POA
HY-185206-5MG
25 mg
£ POA
HY-185206-25MG
About this Product
- SKU:
- HY-185206
- CAS Number:
- 2756388-01-7
- Extra Details:
- BSJ-05-037 is a ITK PROTACs degrader that effectively targets and degrades ITK in T-cell lymphoma cell lines. BSJ-05-037 blocks the activation of the NF-κB/GATA-3 signaling pathway; inhibits PLCγ1 phosphorylation; and reduces the proliferative capacity of T-cell lymphoma cells. BSJ-05-037 enhances the sensitivity of T-cell lymphoma cells to chemotherapy. In mouse models of T-cell lymphoma; BSJ-05-037 induces ITK degradation; reduces GATA-3 expression; decreases tumor volume; and reverses chemotherapy resistance. BSJ-05-037 is applicable to research related to T-cell lymphoma[1][2][3].
- Molecular Weight:
- 1022.20
- Purity:
- 98.31
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture and light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
