PD-1/PD-L1-IN-61
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HY-182047-1EACH
About this Product
- SKU:
- HY-182047
- CAS Number:
- 2983098-90-2
- Extra Details:
- PD-1/PD-L1-IN-61 is a PD-1/PD-L1 interaction inhibitor with a human IC50 of 5.3 nM. PD-1/PD-L1-IN-61 embeds into the hydrophobic pocket at the PD-L1 dimer interface; stabilizing binding through hydrogen bonds and π-π stacking with PD-L1 residues. PD-1/PD-L1-IN-61 acts as an immune activator; enhances immune-killing activity of peripheral blood mononuclear cells against cancer cells; restores T-cell immune function; and promotes IFN-γ secretion. PD-1/PD-L1-IN-61 can be used for the research of triple-negative breast cancer[1].
- Molecular Weight:
- 776.83
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
