BE2012
Product Sizes
50 mg
£ POA
HY-180944-50MG
5 mg
£ POA
HY-180944-5MG
10 mg
£ POA
HY-180944-10MG
25 mg
£ POA
HY-180944-25MG
100 mg
£ POA
HY-180944-100MG
10mM/1mL
£ POA
HY-180944-10MM
About this Product
- SKU:
- HY-180944
- CAS Number:
- 667889-47-6
- Extra Details:
- BE2012; SR8278 (HY-14415) derivative; is a potent and selective REV-ERBα/β Antagonist with EC50 values of 0.285 and 0.346 μM. BE2012 binds to the ligand-binding domain (LBD) of REV-ERB; preventing the receptor from recruiting co-inhibitory factors and thereby releasing the transcriptional repression on downstream target genes. BE2012 can upregulate the expression of myogenic transcription factors Myf5 and Myod; promoting muscle regeneration and repair in acute muscle injury micemodels[1].
- Molecular Weight:
- 293.36
- Purity:
- 99.49
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; stored under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
