Anti-Influenza agent 10
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HY-180269-1EACH
About this Product
- SKU:
- HY-180269
- Extra Details:
- Anti-Influenza agent 10 (Compound 41) is an influenza A virus RNA-dependent RNA polymerase (RdRp) inhibitor. Anti-Influenza agent 10 exhibits potent antiviral activity against A/PR/8/34(H1N1) with an IC50 of 0.29μM and a KD of 4.11 μM. Anti-Influenza agent 10 can inhibit the assembly of the viral RdRp complex by disrupting the protein interaction between PA and PB1 subunits; thereby blocking the transcription and replication of the viral genome. Anti-Influenza agent 10 shows significant broad-spectrum effects on multiple influenza virus strains; such as H3N2; H3N8 and H9N2 with IC50 values of 3.96; 1.91 and 1.45 μM. Anti-Influenza agent 10 can be used for the research of influenza A Virus Infection[1].
- Molecular Weight:
- 478.99
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
