Photosensitizer-8
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HY-180169-1EACH
About this Product
- SKU:
- HY-180169
- CAS Number:
- 3106369-28-9
- Extra Details:
- Photosensitizer-8 (Compound 4); 2-anthrol derivative; is an alkaline phosphatase (ALP)-activatable photosensitizer. Photosensitizer-8 undergoes a phosphate ester hydrolysis reaction in the presence of ALP; rapidly converting into the active photosensitizer 2-anthrol. Photosensitizer-8 exhibits cytotoxicity against ALP-overexpressing cancer cells (HeLa; A549; HCT116) after light exposure; with IC50 values of 14.3 μM; 21.6 μM and 17.5 μM; respectively; while showing no significant cytotoxicity against normal lung fibroblasts (WI-38) (IC50 ≥ 30 μM). Photosensitizer-8 can be used in photodynamic therapy research for ALP-overexpression-related cancers[1].
- Molecular Weight:
- 274.21
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
