EGFR/VEGFR2-IN-10
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HY-179485-1EACH
About this Product
- SKU:
- HY-179485
- Extra Details:
- EGFR/VEGFR2-IN-10 is a selective EGFR; VEGFR2 and COX2 inhibitor with IC50s of 8.5; 68 and 158 nM; respectively. EGFR/VEGFR2-IN-10 induces G1-phase cell cycle arrest in MCF-7 cells. EGFR/VEGFR2-IN-10 increases the Bax/Bcl-2 ratio; upregulates caspase-8; and elevates caspase-9 protein levels; confirming activation of the intrinsic apoptotic pathway. EGFR/VEGFR2-IN-10 demonstrates exceptional therapeutic potential by simultaneously inhibiting tumor proliferation; angiogenesis; and inflammation pathways while maintaining a favorable selectivity profile. EGFR/VEGFR2-IN-10 can be used as a research tool for cervical; liver; colon; and breast cancer studies[1].
- Molecular Weight:
- 532.41
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
