E0199
Product Sizes
50 mg
£ POA
HY-178281-50MG
25 mg
£ POA
HY-178281-25MG
10 mg
£ POA
HY-178281-10MG
5 mg
£ POA
HY-178281-5MG
10mM/1mL
£ POA
HY-178281-10MM
About this Product
- SKU:
- HY-178281
- CAS Number:
- 931928-13-1
- Extra Details:
- E0199 is a novel potent dual-target KV7/NaV modulator that activates the KV7 channel (KV7.2/7.3 (EC50 = 12.78 nM); KV7.2 (EC50 = 0.50 μM); and KV7.5 (EC50 = 27.14 nM) channels) while simultaneously blocks the NaV1.7 (IC50 = 0.52 μM); NaV1.8 (IC50 = 0.24 μM); and NaV1.9 (IC50 = 0.16 μM) channels. E0199 shows a potent analgesic effect without affecting heart and skeletal muscle ion channels critically in a chronic constriction injury (CCI) mouse model. E0199 can be used for Neuropathic pain (NP) research[1].
- Molecular Weight:
- 535.63
- Purity:
- 99.89
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
