CBP/p300-IN-22
Product Sizes
Get quote
£ POA
HY-176251-1EACH
About this Product
- SKU:
- HY-176251
- Extra Details:
- CBP/p300-IN-22 is a selective CBP/EP300-BRD inhibitor with an IC50 of 4 nM. CBP/p300-IN-22 is highly selective over BRD4(1). CBP/p300-IN-22 reduces TNF-α-induced cytokine expression and subsequent immune cell recruitment by inhibiting NF-κB signaling; and has anticancer activity. CBP/p300-IN-22 can be used for the research of rheumatoid arthritis (RA) and other TNF-α-mediated inflammatory conditions[1].
- Molecular Weight:
- 452.46
- References:
- [1]Gosselé KA, et al. Selective CBP/EP300 Bromodomain Inhibitors: Novel Epigenetic Tools to Counter TNF-α-Driven Inflammation. JACS Au. 2025 Jun 5;5(6):2491-2499.
- Research Area:
- Cancer; Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
