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Proteins and Peptides

(E)-Belizatinib

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HY-17603A-1EACH
About this Product
SKU:
HY-17603A
Additional Names:
(E)-TSR-011
CAS Number:
1388225-72-6
Extra Details:
(E)-Belizatinib ((E)-TSR-011)) (compound 36); the (E)-isomer of Belizatinib (HY-17603); is a potent; selective and orally active anaplastic lymphoma kinase (ALK) Inhibitor with an enzymatic IC50 of 0.005 μM and a cellular IC50 of 0.048 μM. (E)-Belizatinib shows >61-fold selectivity over JAK2; SRC; and IGF1R. (E)-Belizatinib shows favorable potency and PK characteristics in rats and dogs. (E)-Belizatinib can be used for ALK-driven cancer research[1].
Molecular Weight:
577.73
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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