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Proteins and Peptides

(Rac)-Timolol-d5 (maleate)

Product Sizes
1 mg
£ POA
HY-17494S-1MG
About this Product
SKU:
HY-17494S
Additional Names:
(Rac)-L-714;465 (maleate); (Rac)-MK 950-d5
CAS Number:
1217260-21-3
Extra Details:
rac Timolol-d5 (maleate) is a labelled racemic (S)-Timolol maleate. (S)-Timolol Maleate (L-714;465 Maleate) is a non-cardioselective hydrophilic β-adrenoceptor blocker. (S)-Timolol Maleate is widely used as standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. (S)-Timolol Maleate can be used for hypertension; angina pectoris and myocardial infarction[1][2][3].
Molecular Weight:
437.52
Purity:
99.0
References:
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Mitrović M, et al. Analytical quality by design development of an ecologically acceptable enantioselective HPLC method for timolol maleate enantiomeric purity testing on ovomucoid chiral stationary phase. J Pharm Biomed Anal. 2020 Feb 20;180:113034.|[3]Wedian F, et al. Simultaneous spectrofluorometric analysis of tablets containing hydrochlorothiazide combined with timolol maleate or amiloride hydrochloride. Acta Pharm. 2020 Sep 1;70(3):373-385.|[4]Sun L, et al. Fractional 2940-nm Er:YAG Laser-Assisted Drug Delivery of Timolol Maleate for the Treatment of Deep Infantile Hemangioma. J Dermatolog Treat. 2020 Feb 11:1-24.
Research Area:
Neurological Disease; Cardiovascular Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C; 3 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
GPCR/G Protein;Neuronal Signaling;Others
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